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Results for "

melanin biosynthesis

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

8

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1098
    Velutin

    		HIF/HIF Prolyl-Hydroxylase Inflammation/Immunology
    Velutin is an aglycone extracted from Flammulina velutipes, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway .
    Velutin
  • HY-163326
    Tyrosinase-IN-25

    		Tyrosinase Cancer
    Tyrosinase-IN-25 (compound 1l) is an inhibitor of tyrosinase and melanin biosynthesis in human melanoma cells .
    Tyrosinase-IN-25
  • HY-161241
    Tyrosinase-IN-23

    		Tyrosinase Cancer
    Tyrosinase-IN-23 (Compd 11m) is a tyrosinase inhibitor with an IC50 of 55.39±4.93 µM. Tyrosinase-IN-23 can be used for research of melanin biosynthesis .
    Tyrosinase-IN-23
  • HY-N12840
    Logmalicid B

    		Others Metabolic Disease
    Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .
    Logmalicid B
  • HY-N9521
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside

    		Others Cancer
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside, a saponin, is isolated from Polaskia chichipe Backbg. 3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside shows ability to inhibit melanin biosynthesis by B16 melanoma cell with inhibitory activity 84.2% at 100μM[1].
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside
  • HY-W725641
    Tricyclazole-d3

    		Bacterial Infection
    Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
    Tricyclazole-d3
  • HY-B0848
    Tricyclazole

    		Bacterial Infection
    Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor and a unique fungicide for control of Pyricularia oryzae on rice .
    Tricyclazole
  • HY-N2902
    Artocarpin

    		Others Cancer
    Artocarpin is an isoprenoid-substituted flavonoid, that can be isolated from the wood of Artocarpus heterophyllus. Artocarpin inhibits melanin biosynthesis in B16 melanoma cells without inhibiting tyrosinase. The presence of the isoprenoid-substituted moiety enhanced the inhibitory activity on melanin production in B16 melanoma cells .
    Artocarpin
  • HY-N12431
    Machilin A

    		Others Cancer
    Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
    Machilin A
  • HY-N4265
    Vinaginsenoside R4

    		Others Inflammation/Immunology
    Vinaginsenoside R4, isolated from the leaves of hydroponic Panax ginseng. It has an inhibitory effect on melanin biosynthesis without any cytotoxic effects on the melan-a cells, and enhances the depigmentation on the zebrafish .
    Vinaginsenoside R4
  • HY-111898
    Epirosmanol

    		Others Cancer
    Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .
    Epirosmanol
  • HY-143450
    Tyrosinase-IN-3

    		Tyrosinase Others
    Tyrosinase-IN-3 (compound 54) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-3 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-3
  • HY-143451
    Tyrosinase-IN-4

    		Tyrosinase Others
    Tyrosinase-IN-4 (compound 34) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-4 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-4
  • HY-143448
    Tyrosinase-IN-1

    		Tyrosinase Others
    Tyrosinase-IN-1 (compound 90) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-1 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-1
  • HY-143449
    Tyrosinase-IN-2

    		Tyrosinase Others
    Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-2
  • HY-126052
    Gnetol

    		COX Tyrosinase HDAC Metabolic Disease Cancer
    Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .
    Gnetol

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